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    My Digital Twin on the Podcast: A look at Fall Risks Based on Real-World-Data

    by Sónia Alves

    Today, I have the privilege of sharing something truly unique: a very special podcast. My digital twin, created using Google’s NotebookLM, recorded a podcast on my behalf. The topic is nothing short of fascinating: our recent publication, which is based on real-world data, explores the relationship between fall risk and actual falls among older adults.

    Imagine this: while our company is in the midst of relocating—unpacking boxes, setting up desks—a podcast on a scientific subject takes shape in parallel. This achievement coincides with the publication of our study in the prestigious JMIR Aging journal (Impact Factor: 5.0), which has peer-reviewed and published our submission.

    Evaluating the prognostic and clinical validity of the Fall Risk Score derived from an AI-based mHealth application for fall prevention: a retrospective real-world data analysis

    Was ist so besonders an diesem Podcast?

    My digital twin engaged in a discussion with one of the authors of the World Fall Guidelines, a globally recognized expert in fall prevention, to explore my recently published study on fall risk assessment. The study investigated an AI-driven mHealth application, the LINDERA Mobility Analysis, designed for fall prevention. This application was deployed in German nursing facilities and calculates a Fall Risk Score (FRS). What makes it unique is its dual approach: the app captures users’ gait parameters through smartphone-based video analysis and incorporates additional risk factors using a structured digital questionnaire.

    Screenshots of the mHealth Application During the Initial Phase of a New Analysis

    The podcast delves into the validity of the FRS and its clinical application. My digital twin, alongside an expert from the World Fall Guidelines, provides an in-depth presentation of the app and its features. They then transition to a discussion about the relationship between the FRS and actual falls, emphasizing the significance of these findings for fall prevention.

    The discussion highlights the Minimum Clinically Important Differences (MCIDs) for changes in the FRS. MCIDs are essential for clinicians to assess whether a change in the FRS following an intervention, such as a training program, is clinically meaningful.

    For example, if a person’s FRS decreases by more than the MCID value of 2.3—say, from 35 to 32—this change indicates a meaningful reduction in fall risk.

    The study also identified critical FRS thresholds, indicating the point at which fall risk increases within a given timeframe. For instance, an FRS above 45% suggests a heightened risk of falling within the next six months.

    The combination of MCIDs and thresholds offers a valuable framework for planning and evaluating fall prevention measures.

    Special Risk Groups

    A particularly interesting segment of the podcast focused on subgroups where significant associations between fall risk and actual falls were observed. Multiple factors such as age, fall history, dementia, gait speed, and the use of walking aids were analyzed.

    The study revealed a significant association between fall risk and slower gait speeds and the use of walking aids. These findings are crucial for identifying high-risk patient groups. For example, individuals with slower gait or reliance on walking aids may require more intensive monitoring and targeted preventive interventions.

    Fall Prevention in Focus: Prioritizing Individual Needs

    While mHealth applications like the one studied can complement fall prevention efforts, it’s essential to recognize their limitations and interpret results within the individual context. Person-centered fall prevention, as recommended by the World Fall Guidelines, must remain the primary focus.

    A heartfelt thank-you goes to all co-authors (Steffen Temme, Seyedamirhosein Motamedi, Marie Kura, Sebastian Weber, Johannes Zeichen, Wolfgang Pommer, André Baumgart) and especially to the 617 subjects whose data made this investigation possible.

    I warmly invite you to listen to the podcast and explore the findings of our study. The connection to care practice is further detailed in our press release.

    Lindera. ACCEPT NO LIMITS.

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